What Are Systemic Enzymes and What Do They Do? 체내효소란 무엇이며 어떤 역할을 하나?
By: Dr. William Wong ND, PhD
The word “systemic” means body wide. Systemic enzymes are those that operate not just for digestion but
체내효소는 단지 음식물의 소화 뿐 만 아니라, 인체장기나 모든기관이 움직이는데 있어서 광범위하게 필요한 것이다.
throughout your body in every system and organ. But let’s take first things first, what is an enzyme?
우선 먼저 효소란 무엇인지에 대하여 부터 알아보기로 하자.
An enzyme is a biocatalyst - something that makes something else work or work faster. Chemical reactions are
효소란 생촉매로서 화학반응을 하게 만드는 것 또는 그 작용을 촉진시키는 물질이다. 일반적으로 화학반응이란 느리게 일어나기
generally slow things, enzymes speed them up. Without enzymes the chemical reactions that make up our life would
쉬운데, 효소는 이런 반응을 아주 빠르게 한다. 효소가 없다면, 인체 내의 화학반응은 너무 느려서 생명을 유지할 수 없을 것이다.
be too slow for life as we know it. (As slow as sap running down a tree in winter). For life to manifest as we know it,
enzymes are essential to speed up the reactions. We have roughly some 3000 enzymes in our bodies and that
우리 몸에는 약3000여개의 효소가 있는데, 이들이 7000가지 넘는 화학반응을 일으키고 있다.
results in over 7000 enzymic reactions. Most of these enzymes are derived or created from what we think of as the
이들 효소의 대부분은 단백질 소화효소로부터 나오는 것으로 알고 있다.
protein digesting enzymes. But while digestion is an important part of what enzymes do, it's almost the absolute last
효소가 체내에서 하는 일로서, 소화활동에 물론 중요한 역할을 하지만 이는 효소가 하는 일로는 거의 끝부분에 해당하는 것이라 하겠다.
function. First and foremost these body wide proteolytic (protein eating) enzymes have the following actions:
무엇보다 중요한 효소의 기능은 다음과 같은 것이다.
Natural Anti-Inflammatory. 자체 염증방어 작용
They are the first line of defense against inflammation. (1,2,3). Inflammation is a reaction by the immune system to an irritation.
효소는 최일선에서 염증에 대항한다. 염증이란 어떤 자극에 대항하려는 면역계의 반응이다.
Let’s say you have an injured right knee. The immune system sensing the irritation the knee is undergoing creates a protein chain
오른쪽 무릎을 다쳤다고 할 때, 그 무릎의 자극을 감지한 면역계에서는 CIC라 부르는 단백질사슬을 만들어낸다.
called a Circulating Immune Complex (CIC for short), tagged specifically for that right knee. (The Nobel Prize in biology was won in
CIC는 오른쪽 무릎으로 내려와서 통증과 빨갛게 붓게 만드는데 이것은 다름아닌 교과서적인 염증의 표시다.
1999 by a scientist who discovered this tagging mechanism). This CIC floats down to the right knee and causes pain, redness and
우선 이것은 유익한 반응이라 하겠는데, 우리 몸의 어느 일부가 다쳤으니 주의하라는 것을 알려주는 신호인 것이다.
swelling are the classic earmarks for inflammation. This at first is a beneficial reaction; it warns us that a part of ourselves is hurt
and needs attention. But, inflammation is self-perpetuating, itself creating an irritation that the body makes CIC’s to in response!
그러나, 염증이란 그치지 않고 지속되므로 그 자체로 자극이 된다. 따라서 우리 몸은 그에 대한 반응으로 CIC를 만들어내는 것이다.
Aspirin, Ibuprofen, Celebrex, Vioxx and the rest of the Non Steroidal Anti Inflammatory Drugs all work by keeping the body from
아스피린, 이부프로펜, 셀레브렉스, 바이옥스 그리고 비스테로이드계 항염증약물들이 CIC를 만들지 못하도록 지원하는 것이다.
making all CIC's. This ignores the fact that some CIC’s are vital to life, like those that maintain the lining of the intestine and those
이것은 그러나 어떤 CIC는 우리 몸 (장과 콩팥의 특정 기능) 에서 반드시 필요로 하는 물질이라는 점을 몰라서 하는 얘기다.
that keep the kidneys functioning! Not to mention the fact that the NSAID’s, along with acetaminophen, are highly toxic to the liver.
Every year 20,000 Americans die from these over the counter drugs and another 100,000 will wind up in the hospital with liver
damage, kidney damage or bleeding intestines from the side effects of these drugs. (4,5).
Systemic enzymes on the other hand are perfectly safe and free of dangerous side effects. They have no LD-50, or toxic dose. (6).
약물들과는 반대로, 체내효소는 완벽하게 안전해서 어떤 위험한 부작용도 없다.
Best of all systemic enzymes can tell the difference between the good CIC’s and the bad ones because hydrolytic enzymes are
lock and key mechanisms and their "teeth" will only fit over the bad CIC’s. So instead of preventing the creation of all CIC’s,
CIC 생성을 방해하는 대신에, 체내효소는 단지 나쁜 것만을 먹어치울 뿐이라서, 염증과 통증을 전반적으로 가라앉게 만든다.
systemic enzymes just “eat” the bad ones and in so doing lower inflammation everywhere. With that, pain is lowered also.
Anti Fibrosis. 섬유질 방지효과
Enzymes eat scar tissue and fibrosis. (7). Fibrosis is scar tissue and most doctors learn in anatomy that it is fibrosis that
효소는 상처자국과 섬유질화 된 것을 먹어치운다. 섬유질화가 결국 사람을 죽게 만든다고 해부학시간에 의사들도 배우고
eventually kills us all. Let me explain. As we age, which starts at 27, we have a diminishing of the bodies’ output of enzymes. This
있다. 대개 27살 정도에 이르면 우리 몸의 효소 생산량은 줄어든다. 우리 몸이 평생동안 한정된 양의 효소만 생산해 낼 수 있기
is because we make a finite amount of enzymes in a lifetime and we use up a good deal of them by the time we are 27. At that
때문인데, 27살 정도가 되면 우리 몸에서는 이미 대부분의 효소를 다 써 버린다는 것이다.
point the body knows that if it keeps up that rate of consumption we’ll run out of enzymes and be dead by the time we reach our
체내효소를 그렇게 계속 소비하면, 나이 40세가 될 즈음에는 효소가 고갈되어 죽어버린다는 것을 우리 몸이 알기 때문에 이를 통제
40’s. (Cystic Fibrosis patients who have virtually no enzyme production to speak of, even as children usually don’t make it past
한다는 뜻이다. (체내효소가 생산이 사실상 없다고 볼 수 있는 Cystic섬유질화 환자의 경우, 애들이도 스무 살을 넘기지 못하는데
their 20’s before they die of the restriction and shrinkage in the lungs from the formation of fibrosis or scar tissue).
이는 섬유질화 또는 상처자국의 조직으로 인하여 페의 심각한 기능제한, 폐의 부피축소가 일어나기 때문이다.
So our body in it's wisdom begins to dole out our enzymes with an eyedropper instead of with a tablespoon; as a result the repair
우리 몸은 인색하게도 효소를 (숟가락 보다는 눈약병으로 사용하듯이) 아주 조금씩만 내어주기 시작한다. 그렇게 되면 우리 몸의
mechanism of the body goes out of balance and has nothing to reduce the over abundance of fibrin it deposits in nearly every thing
복구 시스템에 문제가 생기게 된다.
from simple cuts, to the inside of our internal organs and blood vessels. This is when most women begin to develop things like
fibrocystic breast disease, uterine fibroids, endometriosis, and we all grow arterial sclerotic (meaning scar tissue) plaque, and have fibrin beginning to spider web its way inside of our internal organs reducing their size and function over time. This is why as we age our wounds heal with thicker, less pliable, weaker and very visible scars.
나이를 먹을 수록, 치유된 상처자국이 더 두꺼워지고 유연성을 잃고, 더 약해지고, 눈에도 잘 띄는 이유인 것이다.
If we replace the lost enzymes we can control and reduce the amount of scar tissue and fibrosis our bodies have. As physicians in
잃어버린 효소를 보충해 줌으로서, 상처자국이나 섬유질화 현상을 줄일 수 있게 된다. 점차 미국의 의사들도 알게 된 사실은, 외과
the US are now discovering, even old scar tissue can be “eaten away” from surgical wounds, pulmonary fibrosis, kidney fibrosis
수술로 생긴 오래된 상처자국, pulmonary fibrosis, 콩팥의 섬유질화 또는 몇 년전에 생긴 켈로이드 까지도 효소가 먹어치울 수 있
and even keloids years after their formation. Medical doctors in Europe and Asia have known this and have used orally
다는 것이다. 유럽과 아시아의 의사들은 이것을 알아서 벌써 40년 전부터 효소를 경구투여해 사용하고 있다.
administered enzymes for these situations for over 40 years!
Blood Cleansing. 혈액의 독소제거
The blood is not only the river of life, it is also the river through which the cells and organs dispose of their garbage and dead
material. Enzymes improve circulation by eating the excess fibrin that causes blood to sometimes get as thick as catsup or yogurt, creating the perfect environment for the formation of clots. All of this material is supposed to be cleared by the liver on its "first pass", or the first time it goes through but given the sluggish and near toxic or toxic states of everyone's liver these days that seldom happens. So the sludge remains in the blood waiting for the liver to have enough free working space and enough enzymes to clean the trash out of the blood. This can take days, and in some cases, weeks! (8).
When systemic enzymes are taken, they stand ready in the blood and take the strain off of the liver by:
- Cleaning excess fibrin from the blood and reducing the stickiness of blood cells. These two actions minimize the leading causes of stroke and heart attack causing blood clots. (8).
- Breaking dead material down small enough that it can immediately pass into the bowel. (8).
- Cleanse the FC receptors on the white blood cells improving their function and availability to fight off infection. (9).
And here we come to the only warning we have to give concerning the use of systemic enzymes - don't use the product if you are a hemophiliac or are on prescription blood thinners like Coumadin, Heparin and Plavix, without direct medical supervision. The enzymes cause the drugs to work better so there is the possibility of thinning the blood too much.
Immune System Modulating. 자가면역질환을 다스린다
Enzymes are adaptogenic seeking to restore a steady state to the body. (9). When the immune system is running low we become susceptible to infectious disease, when it’s cranked up too high then the system creates antibodies that attack it's own tissues as are seen in the auto immune diseases of MS, Rheumatoid Arthritis, and Lupus. Here the enzymes will tone down immune function and eat away at the antibodies the immune system is making to attack its bodies own tissue.
Virus Fighting. 바이러스 퇴치
Viruses harm us by replicating in our bodies. To do this a virus must bond itself to the DNA in our cells through the medium of its exterior protein cell wall. Anything that disrupts that cell wall inhibits the ability of viral replication by rendering individual viruses inert. (10,11). Systemic enzymes can tell the difference between the proteins that are supposed to be in your body and those that are foreign or not supposed to be there, (again the enzyme lock and key mechanism).
Note
Many in the States have learned in school that enzymes are too big a protein to be absorbed through the gut.
미국내 학교에서는 효소가 너무 큰 단백질이라서 인체에서 흡수되기 어렵다고 가르쳐 왔다.
The pioneering research done in the US by Dr. Max Wolf (MD & PhD x7) at Columbia University in the 40’s through the 70’s has
1940 ~ 70년대, 미국 컬럼비아 대학 맥스 울프 박사가 주도한 시범적인 연구결과에 대하여 대부분의 의사들은 주목하지 않았다
not made it to the awareness of most doctors. There are currently over 200 peer reviewed research articles dealing with the
경구투여한 체내효소의 흡수, 활용 및 치료효과 에 대하여는 현재 200여 연구논문이 있다. 'Pub Med' 라는 사이트에서,
absorption, utilization and therapeutic action of orally administered systemic enzymes. A search through Pub Med using the key
'serrapeptase, papain, bromelain, trypsin, chymo trypsin, nattokinase 와 systemic enzyme 등의 단어를 입력해 보면
words: serrapeptase, papain, bromelain, trypsin, chymo trypsin, nattokinase and systemic enzyme will yield some of the extensive
이들 체내효소의 흡수,체내활용및 치료효과에 대한 그간의 연구결과를 검색해 볼 수 있다. 이미 유럽중부, 일본등지에서는 40년 이상 체내효소를 치료목적으로 사용해 온 역사를 갖고 있다.
work. Systemic enzymes now have a four-decade plus history of widespread medical use in central Europe and Japan.
References
1) Carroll A., R.: Clinical examination of an enzymatic anti-inflammatory agent in emergency surgery. Arztl. Praxis 24 (1972), 2307.
2) Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic
inflammation of otorhinolaryngology pathology: a multicentre, double blind,
randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment of breast engorgement with Serrapeptase: a randomized double blind controlled trial. Singapore Med J. 1989:30(l):48-54.
4) Celebrex article Wall Street Journal 19 April 1999.
5) No author listed: Regular Use of Pain Relievers Can Have Dangerous Results. Kaleidoscope Interactive News, American Medical Association media briefing. July 24, 1997.
6) Enzymes ñ A Drug of the Future, Prof. Heinrich Wrba MD and Otto Pecher MD. Published 1993 Eco Med.
7) Kakinumu A. et al.: Regression of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.
8) Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology. Klin Wschr. 65 (1987), 994.
9) Kunze R., Ransberger K., et at: Humoral immunomodulatory capasity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991.
10) Jager H.: Hydrolytic Enzymes in the therapy of HIV disease. Zeitschr. Allgemeinmed., 19 (1990), 160.
11) Bartsch W.: The treatment of herpes zoster using proteolytic enzymes. Der Informierte Arzt. 2 (1974), 424-429.